SFC-50
Preparative separations on small columns
The SFC-50 from Sepiatec is a compact and easy-to-use chromatography system for preparative separations on small columns by means of supercritical fluid chromatography (SFC). The system offers the comprehensive benefits of SFC technology, such as faster separations, lower costs due to reduced consumption of organic solvents, as well as being more environmentally friendly at increased safety.
The SFC-50 is equipped with two 400 bar high-pressure pumps with 30 ml pump heads. The total flow – at a modifier portion of 40 % – amounts to 50 ml/min. This way, chromatography columns with inner diameters ranging from 4 to 16 mm, and a length of up to 250 mm can be used.
The column oven, containing the chromatography columns together with the injection valve and the UV flow cell, is heatable up to 70° C so that a uniform temperature is ensured. The SFC-50 system is equipped with 9 gas-liquid-separators (1 for waste) for precise separation of chiral compounds.
As fractions are collected in unpressurized state, not only safety is increased, but also handling is simplified, and limitations with respect to the size of fraction volumes do not exist. This option proves to be extremely convenient when working with stack injections.
As the dimensions of the SFC-50 together with the integrated system controller and 15.6” touch screen amount to only 56 x 60 x 88 cm (W x D x H) this system requires a minimum of space in the laboratory. A separate computer or monitor is not necessary.
The equipment of the SFC-50 system includes
- a high pressure pump for CO2
- a high pressure pump for modifiers
- an adjustable back pressure regulator
- a syringe pump for sample injection
- a diode array detector (PDA)
- an integrated system controller
- a 15.6“ touch screen
- USB connectors, Ethernet and HDMI connector
- the Prep SFC control software
The equipment can be expanded with optional accessories
- Add-on pump for separations with low modifier portions
- ELSD detector
- Mass spectrometer