Prep SFC M5
Versatile SFC System for Chiral and Achiral Separations
Sepiatec’s Prep SFC M5 system is a preparative system for separating chiral and achiral samples using supercritical fluid chromatography.
The Prep SFC M5 system consists of the main module and the collector module. Both modules form a functional unit that can be configured in a variety of ways with different equipment.
The main module can be equipped with up to three high pressure pumps, a CO2 pump, a modifier pump and an optional add-on pump for separations with low modifier portions. The available options include CO2 and modifier pumps with 30 ml pump heads, 400 bar (Prep SFC M5-50) or CO2 and modifier pumps with 150 ml pump heads, 400 bar (Prep SFC M5-250).
The integrated auto sampler can accommodate two standard or two deep well microtiter plates with 24 wells and a volume of 10 ml each or racks with up to 60 sample vials with a volume of 1.5 ml each.
The heatable column oven contains up to 10 separation columns with internal diameter of 4 to 30 mm and a length of 250 mm.
Standard equipment in the main module is a UV detector for measuring in the range of 190 – 500 nm. Other detectors, such as a DAD or an ELSD, can also be connected.
An integrated system controller and a 15.6” TFT touch screen are used to input all data for sample separations. No additional computer is needed, reducing the space required for the Prep SFC M5 system to a width of just 92 cm.
The post heater and the back pressure regulator are integrated within the collector module. The continuously operating gas-liquid separator is located at the front of the collector module; it removes residual CO2 from the isolated compounds.
The Prep SFC M5 system can be fitted with a carousel fraction collector which can accommodate collection vessels with volumes ranging from 10 to 500 ml.
Alternatively, an XY-fraction collector for vials with volumes of 10 or 60 ml is available. A total of up to 195 fractions can be collected.
|Solvents||CO2 and organic solvents|
|Number of modifier solvents||1 standard, max. 4 with optional selection valve|
|Operating pressure||Up to 300 bar, back pressure regulator online adjustable|
|Autosampler||2 standard microtiter plates or 2 deep well MTP with 24 wells 10 ml each, racks with 60 vials 1.5 ml or 24 vials 5 ml each|
|Injection||Partial loop with syringe pump|
|Column oven||Ambient temperature to 70° C, 10 columns|
|UV detector||Wavelength range 190 to 500 nm|
|Other detectors||DAD, ELSD or mass spectrometer optional|
Carousel fraction collector: fraction volumes 10 to 500 ml
XY-fraction collector: 72 vials 60 ml or 195 vials 10 ml,
custom made fraction collectors available on request
|Software||Prep SFC control software|
|System controller||Integrated controller, Windows 10|
|Touch screen||15.6” touch screen, 16:9 format|
|Connections||3 USB ports, Ethernet, HDMI|
|Dimensions||92 x 60 x 88 cm (W x D x H), with XY fraction collector 97 cm in width|
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